The game stars Wex Major, a young male who gets lost in an unfamiliar galaxy.[4] He eventually meets up with eight other off-beat, strange adventurers, and becomes the leader of the group, which they dub the "Wild 9". The "Nine" consists of "Nitro", who has serious allergy problems and explodes once coming across said allergens, "Pokkit", who has a special jacket with an infinite amount of pockets full of an infinite number of things, "Pilfer", a lizard with thousands of separate personalities, "Volstagg", a strong person with gorilla and gazelle DNA, "Crystal", who is solar powered and has a body made of crystal with living hair, "Boomer McTwist", who has powers from wearing the kilt of her Scottish superhero father, "MacSheen", who is adept with tools but is rather hormonal, "Henry", a being made entirely out of living water and "B'Angus"(B is silent), who looks similar to a chihuahua, and lives inside the Rig item, providing advice for Wex. The game's main antagonist is the evil Karn, a being who is 376 years old and desires to use the "Rig" item as a method of enslaving and controlling the inhabitants of the universe. Karn kidnaps the rest of the "Wild 9" crew, leaving it up to Wex to rescue them and ultimately defeat Karn.